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 IMSI; Modern Fertility Treatment to help in fighting with Infertility Issues


The shot of bat-to-ball creates excitements sometimes if played scoring well, but grows wrinkles also over each and everyone’s face after it scores nil. So the medical term – medicine has its play important when to wipe out the word (disease) out of human’s dictionary. Attributed to have been an only assurance of healthy lifestyle, the medicine leaves no If’s and But’s to assure one breathe in hale and hearty lifestyle.

Therefore, it may be seen people ought to appear wrinkle-free to their every kind of medical condition. In India, there are many medical addresses answerable to coming with modern and effective medical treatments, so believe on us availing wide range of fertility treatments such as IMSI (Intracytoplasmic Morphologically Selected Sperm Injection)


lab faqs IMSI

IMSI stands as a technique where sperm samples are examined under a microscope which is almost 6000 times more powerful than normal ICSI microscopes. Yes, this technique permits us to choose the very best quality sperm, without any defects, to inject into the patient, thus enhancing our rates of implantation and pregnancy.
As some studies recommend that using this technique decides on better quality sperm and results in the higher pregnancy rates and lower miscarriage rates compared to conventional ICSI.
In conventional ICSI, the embryologist chooses the most normal-looking motile sperm making use of a microscope that enlarges the sample up to 400 times. Sure! IMSI materializes itself as a variation of ICSI that utilizes a high power light microscope to blow up the sperm sample over 6000 times. This lets the embryologist to become aware of delicate structural alterations in sperm that a usual microscope could not detect. Sperm get then selected which have the most normally-shaped nuclei.

  • Those with sperm revealing to high-degree of DNA fragmentation or enlarged irregular spermatozoa, conditions which often go with oligoasthenospermia;
  • Patients with prior two IVF or ICSI failures;
  • Couples with inexplicable infertility as it has been explained that IMSI results in better egg fertilization rates, better quality embryos, better rate of blastocyst formation and then better pregnancy rates;
  • Couples bearing recurrent IVF failures or recurrent biochemical pregnancies/miscarriages.
At us, IMSI is recommended for all the couples enduring an “In Vitro” fertilization treatment with Intracytoplasmic sperm injection, but particularly for those couples whose sperm samples demonstrate an oligo-terato-astenozoospermia. Also it is recommended for those who have already undergone several “In Vitro” fertilization treatments without success.
In IVF, eggs are produced from the female partner and left in a dish with sperm cells from the male partner. These sperm cells require to be strong enough to go for a dip to the eggs, go in their outer layers and fertilize them.

IMSI and ICSI do not trust in the sperm cells’ capability to execute this – both techniques provide the sperm cells an assisting hand to attain the inner layer of the egg. Where IMSI varies from ICSI, though, is that during IMSI, the embryologist performing the procedure makes use of an very high-powered microscope to decide on the sperm cells with the best morphological quality to be injected into the eggs.

As the UK’s Times online reported on July 7, 2008, that IMSI involves “observing sperm under a high-magnification microscope, about five times more influential than normal laboratory equipment, to choose those with a form and size that points to good genetic quality.”

Based on the Italian study stated above, involving 446 couples in which the male was infertile but the woman had no perceivable fertility problems, the pregnancy rate among the IMSI couples was 32.9% as resisted to 26.5% among the couples who made use of ICSI.

IMSI starts with usual IVF procedure. The female partner is provided ovulation-inducing drugs, and the resulting mature eggs are then produced from her ovaries and arranged for fertilization in the laboratory. The embryologist will then make use of the high-powered microscope to inspect the male partner’s semen sample.

Then, he uses a long, thin, hollow needle to lift up the preferred sperm cell. He holds the egg cell in a particular pipette, and then uses the needle to shove the sperm cell through the outer shell of the egg and into its inner area, where fertilization could happen. The eggs and sperm are then left for 24 hours, during with fertilization is expected to take place. If this is certainly what occurs, the now fertilized eggs are transferred back to the woman’s uterus where hopefully in any case one will implant, resulting in a pregnancy.

Experts say that IMSI is considerably more expensive to carry out than ICSI, owing to the need for focused training and exclusive state-of-the-art equipment. Also there is the possibility of a higher risk of many pregnancies happening from IMSI than from ICSI.
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